122 Increased risk of actinic keratosis and non-melanoma skin cancer in patients with rosacea: A nationwide population-based retrospective cohort study from South Korea

The association between rosacea and skin cancer remains inconclusive with conflicting reports. In this nationwide population-based retrospective cohort study we aimed to determine the risk of in patients rosacea. A (n = 11,420) was formulated evaluated from 2010 2019. incidence rate ratios actinic keratosis, (malignant melanoma[MM] non-melanoma cancer[NMSC]), gastric, colorectal, liver were analyzed comparison matched control group, multivariable stratified Cox proportional hazards model analysis conducted. keratosis increased group compared (adjusted hazard ratio[aHR], 6.05; 95% confidence interval[CI], 3.63-10.09). NMSC also (aHR, 2.66; CI, 1.53-4.61). MM, colorectal or 1.69; 0.25-11.37, aHR, 0.81; 0.59-1.10, 0.91; 0.69-1.18, 1.32; CI 0.89-1.95, respectively) not increased. Our reveals an cancer, particularly NMSC,